CHEMOTHERAPY FOR GASTRIC CANCER REVIEW



Chemotherapy For Gastric Cancer Review

Review Chemotherapy in Elderly Patients with Gastric Cancer. The role of extended lymphadenectomy in the treatment of gastric cancer remains controversial, despite a preponderance of data from large, randomized trials. Surgical lymph node levels are usually classified by the Japanese Gastric Cancer Association system and are used to determine the extent of lymphadenectomy needed., Other chemotherapy drugs used to treat gastric cancer include etoposide and irinotecan. Radiation. Radiation therapy can be used to destroy small traces of cancer that could not be seen and removed during surgery. A type of radiation called “external beam” ….

Stomach Cancer Chemotherapy Gastric Cancer Chemo

Radiotherapy in the Management of Gastric Cancer. Jul 11, 2013 · No standard adjuvant or palliative chemotherapy regimen has been internationally approved for patients with advanced gastric cancer. Adjuvant chemoradiotherapy is administered prior to surgery and is used in the Unitied States, and intensified chemotherapy is administered prior to and after surgery and is used in Europe., Feb 27, 2019 · Treatment decisions should be made with a multidisciplinary team and based on the following: Stage of disease Surgical fitness of the patient The patient’s preference Patient comorbidities Stage 0 to IA Endoscopic mucosal resection or surgery is primary treatment for early-stage gastric cancer. Complete surgical resection offers potential fo....

Pre-Operative Chemotherapy for Gastric Cancer Article В· Literature Review in The Journal of international medical research 37(5):1259-66 В· October 2009 with 25 Reads How we measure 'reads' Dec 01, 2019В В· The current therapeutic strategy for locally advanced gastric cancer is multidisciplinary with surgical procedure as the core. 1 Since the MAGIC (Medical Research Council Adjuvant Gastric Infusional Chemotherapy) trial, neoadjuvant chemotherapies for gastric cancer have been widely accepted. 2 Possible advantages include better tolerance, tumor

Dec 12, 2019 · Background. Marsdenia tenacissima extract (MTE) is a phytochemical widely used as complementary therapy in cancer care. This systematic review was conducted to investigate the anticancer and detoxification effects of MTE, as an adjuvant therapy to … Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving combination chemotherapy and pembrolizumab may work better in treating patients with gastric or gastroesophageal junction cancer.

IP chemotherapy can be a more effective treatment for stomach cancer than chemotherapy drugs taken by mouth or through an IV. Targeted Therapies. MSK experts are currently assessing the effectiveness of using targeted therapies for stomach cancer. Certain agents have shown promise in blocking the development and growth of tumors. Unlabelled: The five years survival rate for patients with gastric cancer is 15-25%. With the aim of improving survival, chemotherapy has been used in different adjuvant settings.

Aug 29, 2017В В· Gastric cancer is the fifth most common cancer worldwide. In "Western" countries, most people are either diagnosed at an advanced stage, or develop a relapse after surgery with curative intent. In people with advanced disease, significant benefits from targeted therapies are currently limited to HER-2 positive disease treated with trastuzumab, in combination with chemotherapy, in first-line. GASTRIC CANCER TREATMENT REGIMENS (Part 1 of 6) Clinical Trials: The NCCN recommends cancer patient participation in clinical trials as the gold standard for treatment. Cancer therapy selection, dosing, administration, and the management of related adverse events can be a complex process that should

Jun 29, 2019 · Introduction. Gastric cancer is the fifth commonest cancer and remains the world’s third leading cause of cancer mortality. 1 Surgery is the mainstay of curative treatment in stage I to III gastric cancers. However, more than half of the patients at diagnosis are … Sep 10, 2018 · Daniel Catenacci, MD: My initial impression of this case is that it is a typical presentation for gastric cancer, presenting with vague symptoms: fatigue, anorexia, some weight loss, and mild abdominal pain. Eventually the patient gets worked up to have an upper endoscopy and is found to have a mass in the distal stomach; confirmed to be a stomach cancer.

Other chemotherapy drugs used to treat gastric cancer include etoposide and irinotecan. Radiation. Radiation therapy can be used to destroy small traces of cancer that could not be seen and removed during surgery. A type of radiation called “external beam” … Dec 01, 2019 · The current therapeutic strategy for locally advanced gastric cancer is multidisciplinary with surgical procedure as the core. 1 Since the MAGIC (Medical Research Council Adjuvant Gastric Infusional Chemotherapy) trial, neoadjuvant chemotherapies for gastric cancer have been widely accepted. 2 Possible advantages include better tolerance, tumor

Review of adjuvant chemotherapy for gastric cancer

chemotherapy for gastric cancer review

The diagnosis and management of gastric cancer The BMJ. IP chemotherapy can be a more effective treatment for stomach cancer than chemotherapy drugs taken by mouth or through an IV. Targeted Therapies. MSK experts are currently assessing the effectiveness of using targeted therapies for stomach cancer. Certain agents have shown promise in blocking the development and growth of tumors., Jul 11, 2013В В· No standard adjuvant or palliative chemotherapy regimen has been internationally approved for patients with advanced gastric cancer. Adjuvant chemoradiotherapy is administered prior to surgery and is used in the Unitied States, and intensified chemotherapy is administered prior to and after surgery and is used in Europe..

Neoadjuvant Chemotherapy for Gastric Cancer

chemotherapy for gastric cancer review

Neoadjuvant chemotherapy in advanced gastric and esophago. 1. Introduction. Gastric cancer (GC) is a major public health problem and is the second most prominent cause of cancer-related death globally [].The incidence of GC, however, dramatically varies across different geographical areas, with the highest rates in Japan, China, other Far Eastern countries, Russia, Middle Eastern area, and in the Pacific coast of the South American continent, and the https://en.m.wikipedia.org/wiki/Cancer_of_the_oesophagus Jul 01, 1995 · Controlled randomized studies that compared surgery alone to adjuvant chemotherapy for gastric cancer were reviewed. The amount of residual tumor after surgery, selection of drug regimens, compliance with drug administration, and trial design seem ….

chemotherapy for gastric cancer review

  • Efficacy of capecitabine and oxaliplatin versus S-1 as
  • Gastric Cancer Treatment Update
  • Adjuvant Chemotherapy for Gastric Cancer with S-1 an Oral

  • Jan 31, 2018В В· Neoadjuvant chemotherapy (NAC) is extensively used in the treatment of patients with gastric cancer (GC), particularly in high risk, advanced gastric cancer. Previous trials testing the efficacy of NAC have reported inconsistent results. This study compares the combined use of NAC and surgery with surgery alone for GC by using a meta-analytic approach. We performed an electronic search of For example, mutations in the genes BRCA1 and BRCA2 have long been associated with breast and ovarian cancers, but a recent review of medical literature concluded that BRCA2 mutation carriers face double the risk of developing gastric cancer and people with BRCA1 mutations have a …

    Sep 16, 2019В В· Gastric cancer during pregnancy is extremely rare and data on optimal treatment and possible chemotherapeutic regimens are scarce. The aim of this study is to describe the obstetric and maternal outcome of women with gastric cancer during pregnancy and review the literature on antenatal chemotherapy for gastric cancer. Material and methods Introduction. Even in after curative surgery and adequate linfoadenectomy the survival of advanced gastric cancer (AGC) remains poor. At present some data have been published on the effects of NACT and perioperative chemotherapy on AGC and Esophago-gastric cancer (EGC) but not definitive ones.

    Pre-Operative Chemotherapy for Gastric Cancer Article В· Literature Review in The Journal of international medical research 37(5):1259-66 В· October 2009 with 25 Reads How we measure 'reads' The role of extended lymphadenectomy in the treatment of gastric cancer remains controversial, despite a preponderance of data from large, randomized trials. Surgical lymph node levels are usually classified by the Japanese Gastric Cancer Association system and are used to determine the extent of lymphadenectomy needed.

    Jul 11, 2013В В· No standard adjuvant or palliative chemotherapy regimen has been internationally approved for patients with advanced gastric cancer. Adjuvant chemoradiotherapy is administered prior to surgery and is used in the Unitied States, and intensified chemotherapy is administered prior to and after surgery and is used in Europe. Introduction. Even in after curative surgery and adequate linfoadenectomy the survival of advanced gastric cancer (AGC) remains poor. At present some data have been published on the effects of NACT and perioperative chemotherapy on AGC and Esophago-gastric cancer (EGC) but not definitive ones.

    May 05, 2010 · Data Sources Data from all RCTs comparing adjuvant chemotherapy with surgery alone in patients with resectable gastric cancer. We searched MEDLINE (up to 2009), the Cochrane Central Register of Controlled Trials, the National Institutes of Health trial registry, and published proceedings from major oncologic and gastrointestinal cancer meetings. Jul 01, 1995 · Controlled randomized studies that compared surgery alone to adjuvant chemotherapy for gastric cancer were reviewed. The amount of residual tumor after surgery, selection of drug regimens, compliance with drug administration, and trial design seem …

    Other chemotherapy drugs used to treat gastric cancer include etoposide and irinotecan. Radiation. Radiation therapy can be used to destroy small traces of cancer that could not be seen and removed during surgery. A type of radiation called “external beam” … Sep 16, 2019 · Gastric cancer during pregnancy is extremely rare and data on optimal treatment and possible chemotherapeutic regimens are scarce. The aim of this study is to describe the obstetric and maternal outcome of women with gastric cancer during pregnancy and review the literature on antenatal chemotherapy for gastric cancer. Material and methods

    chemotherapy for gastric cancer review

    Introduction. Even in after curative surgery and adequate linfoadenectomy the survival of advanced gastric cancer (AGC) remains poor. At present some data have been published on the effects of NACT and perioperative chemotherapy on AGC and Esophago-gastric cancer (EGC) but not definitive ones. Aug 08, 2019В В· Experts review the role of immunotherapy in gastric cancer and review studies KEYNOTE-062, KEYNOTE-061, and KEYNOTE-181.

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    Immune checkpoint inhibition in gastric cancer A

    chemotherapy for gastric cancer review

    Assessment of Laparoscopic Distal Gastrectomy After. The positive impact of such therapies on survival in patients with resected gastric cancer has become clearer over time, although there is no consensus as to the best approach. This topic review will focus on adjuvant and neoadjuvant therapies for noncardia gastric cancer., PURPOSE This systematic review and meta-analysis were performed to assess the efficacy and tolerability of chemotherapy in patients with advanced gastric cancer. METHODS Randomized phase II and III clinical trials on first-line chemotherapy in advanced gastric cancer were identified by electronic searches of Medline, Embase, the Cochrane Controlled Trials Register, and Cancerlit; hand searches.

    Chemotherapy of gastric cancer SpringerLink

    Adjuvant Chemotherapy for Gastric Cancer with S-1 an Oral. Jan 31, 2018В В· Neoadjuvant chemotherapy (NAC) is extensively used in the treatment of patients with gastric cancer (GC), particularly in high risk, advanced gastric cancer. Previous trials testing the efficacy of NAC have reported inconsistent results. This study compares the combined use of NAC and surgery with surgery alone for GC by using a meta-analytic approach. We performed an electronic search of, Background Advanced gastric cancer can respond to S-1, an oral fluoropyrimidine. We tested S-1 as adjuvant chemotherapy in patients with curatively resected gastric cancer. Methods Patients in Japa....

    Nov 06, 2019 · Background and Aim: Although the effect of neoadjuvant chemotherapy in gastric cancer has been extensively studied, the data of survival benefit are still controversial. The purpose of … Gastric cancer is a highly fatal malignancy, and surgery alone often does not provide a cure, even for relatively early stages of disease. Various approaches have been adopted around the world to improve surgical outcomes; however, there currently is no global consensus with regard to the extent of surgery or the timing and choice of chemotherapy and radiation.

    Sep 10, 2018В В· Daniel Catenacci, MD: My initial impression of this case is that it is a typical presentation for gastric cancer, presenting with vague symptoms: fatigue, anorexia, some weight loss, and mild abdominal pain. Eventually the patient gets worked up to have an upper endoscopy and is found to have a mass in the distal stomach; confirmed to be a stomach cancer. Chemotherapy for Stomach Cancer Chemotherapy (chemo) uses anti-cancer drugs that are injected into a vein or given by mouth as pills. These drugs enter the bloodstream and reach all areas of the body, making this treatment useful for cancer that has spread to organs beyond where it started.

    Jun 29, 2019 · Introduction. Gastric cancer is the fifth commonest cancer and remains the world’s third leading cause of cancer mortality. 1 Surgery is the mainstay of curative treatment in stage I to III gastric cancers. However, more than half of the patients at diagnosis are … Other chemotherapy drugs used to treat gastric cancer include etoposide and irinotecan. Radiation. Radiation therapy can be used to destroy small traces of cancer that could not be seen and removed during surgery. A type of radiation called “external beam” …

    Jul 01, 1995 · Controlled randomized studies that compared surgery alone to adjuvant chemotherapy for gastric cancer were reviewed. The amount of residual tumor after surgery, selection of drug regimens, compliance with drug administration, and trial design seem … Unlabelled: The five years survival rate for patients with gastric cancer is 15-25%. With the aim of improving survival, chemotherapy has been used in different adjuvant settings.

    Aug 08, 2019В В· Experts review the role of immunotherapy in gastric cancer and review studies KEYNOTE-062, KEYNOTE-061, and KEYNOTE-181. IP chemotherapy can be a more effective treatment for stomach cancer than chemotherapy drugs taken by mouth or through an IV. Targeted Therapies. MSK experts are currently assessing the effectiveness of using targeted therapies for stomach cancer. Certain agents have shown promise in blocking the development and growth of tumors.

    IP chemotherapy can be a more effective treatment for stomach cancer than chemotherapy drugs taken by mouth or through an IV. Targeted Therapies. MSK experts are currently assessing the effectiveness of using targeted therapies for stomach cancer. Certain agents have shown promise in blocking the development and growth of tumors. Purpose This systematic review and meta-analysis were performed to assess the efficacy and tolerability of chemotherapy in patients with advanced gastric cancer. Methods Randomized phase II and III clinical trials on first-line chemotherapy in advanced gastric cancer were identified by electronic searches of Medline, Embase, the Cochrane Controlled Trials Register, and Cancerlit; hand searches

    Gastric cancer is the fifth most common cause of cancer and the third leading cause of cancer-related death worldwide (7,8). The incidence and mortality of gastric cancer is disproportionately varied by geographic region, with a higher rate in Eastern Asian countries and a … The positive impact of such therapies on survival in patients with resected gastric cancer has become clearer over time, although there is no consensus as to the best approach. This topic review will focus on adjuvant and neoadjuvant therapies for noncardia gastric cancer.

    Chemotherapy in Advanced Gastric Cancer: A Systematic Review and Meta-Analysis Based on Aggregate Data Anna D. Wagner, Wilfried Grothe, Johannes Haerting, Gerhard Kleber, Axel … Background Advanced gastric cancer can respond to S-1, an oral fluoropyrimidine. We tested S-1 as adjuvant chemotherapy in patients with curatively resected gastric cancer. Methods Patients in Japa...

    Nov 04, 2013 · Who gets gastric cancer? Epidemiological data from the American Cancer Society suggest that gastric cancer is the fourth most common cancer in men (after lung, prostate, and colorectal cancer) and the fifth most common cancer in women (after breast, cervical, colorectal, and lung cancer) globally.3 Gastric cancer accounts for 8% of the total number of cases of cancer and 10% of annual … Dec 18, 2019 · Gastric cancer is the fifth most common cancer and the third leading cause of cancer death worldwide, accounting for over 1,000,000 newly diagnosed cancer patients and over 783,000 cancer-related deaths annually [].Radical gastrectomy with extended lymphadenectomy (D2 gastrectomy) is the standard of care for gastric cancer in many countries in East Asia [2, 3].

    For example, mutations in the genes BRCA1 and BRCA2 have long been associated with breast and ovarian cancers, but a recent review of medical literature concluded that BRCA2 mutation carriers face double the risk of developing gastric cancer and people with BRCA1 mutations have a … Jun 29, 2019 · Introduction. Gastric cancer is the fifth commonest cancer and remains the world’s third leading cause of cancer mortality. 1 Surgery is the mainstay of curative treatment in stage I to III gastric cancers. However, more than half of the patients at diagnosis are …

    Dec 01, 2019 · The current therapeutic strategy for locally advanced gastric cancer is multidisciplinary with surgical procedure as the core. 1 Since the MAGIC (Medical Research Council Adjuvant Gastric Infusional Chemotherapy) trial, neoadjuvant chemotherapies for gastric cancer have been widely accepted. 2 Possible advantages include better tolerance, tumor Nov 06, 2019 · Background and Aim: Although the effect of neoadjuvant chemotherapy in gastric cancer has been extensively studied, the data of survival benefit are still controversial. The purpose of …

    Review Chemotherapy in Elderly Patients with Gastric Cancer

    chemotherapy for gastric cancer review

    Settling the Stomach Emerging Treatments for Gastric Cancer. Aug 29, 2017В В· Gastric cancer is the fifth most common cancer worldwide. In "Western" countries, most people are either diagnosed at an advanced stage, or develop a relapse after surgery with curative intent. In people with advanced disease, significant benefits from targeted therapies are currently limited to HER-2 positive disease treated with trastuzumab, in combination with chemotherapy, in first-line., Jul 13, 2017В В· Efficacy and safety of taxane-based systemic chemotherapy of advanced gastric cancer: A systematic review and meta-analysis in the first-line treatment of metastatic gastric cancer.

    chemotherapy for gastric cancer review

    Efficacy of capecitabine and oxaliplatin versus S-1 as. Gastric cancer is a highly fatal malignancy, and surgery alone often does not provide a cure, even for relatively early stages of disease. Various approaches have been adopted around the world to improve surgical outcomes; however, there currently is no global consensus with regard to the extent of surgery or the timing and choice of chemotherapy and radiation., Pre-Operative Chemotherapy for Gastric Cancer Article В· Literature Review in The Journal of international medical research 37(5):1259-66 В· October 2009 with 25 Reads How we measure 'reads'.

    Adjuvant Chemotherapy for Gastric Cancer with S-1 an Oral

    chemotherapy for gastric cancer review

    Unresectable Metastatic Gastric Cancer Targeted Oncology. IP chemotherapy can be a more effective treatment for stomach cancer than chemotherapy drugs taken by mouth or through an IV. Targeted Therapies. MSK experts are currently assessing the effectiveness of using targeted therapies for stomach cancer. Certain agents have shown promise in blocking the development and growth of tumors. https://nlp.cs.nyu.edu/meyers/controversial-wikipedia-corpus/english-html/main/main_0107.html Key words: Gastric cancer; Chemotherapy; Elderly; Review Introduction Gastric cancer (GC) is one of the most frequent malignant diseases, accounting for about 961000 new cases worldwide every year and the third leading cause of cancer-related death [1]. It is the fourth most common cancer behind lung, prostate, and colorectal cancer in men and.

    chemotherapy for gastric cancer review


    Jan 31, 2018В В· Neoadjuvant chemotherapy (NAC) is extensively used in the treatment of patients with gastric cancer (GC), particularly in high risk, advanced gastric cancer. Previous trials testing the efficacy of NAC have reported inconsistent results. This study compares the combined use of NAC and surgery with surgery alone for GC by using a meta-analytic approach. We performed an electronic search of Purpose This systematic review and meta-analysis were performed to assess the efficacy and tolerability of chemotherapy in patients with advanced gastric cancer. Methods Randomized phase II and III clinical trials on first-line chemotherapy in advanced gastric cancer were identified by electronic searches of Medline, Embase, the Cochrane Controlled Trials Register, and Cancerlit; hand searches

    Jan 31, 2018 · Neoadjuvant chemotherapy (NAC) is extensively used in the treatment of patients with gastric cancer (GC), particularly in high risk, advanced gastric cancer. Previous trials testing the efficacy of NAC have reported inconsistent results. This study compares the combined use of NAC and surgery with surgery alone for GC by using a meta-analytic approach. We performed an electronic search of Other chemotherapy drugs used to treat gastric cancer include etoposide and irinotecan. Radiation. Radiation therapy can be used to destroy small traces of cancer that could not be seen and removed during surgery. A type of radiation called “external beam” …

    Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving combination chemotherapy and pembrolizumab may work better in treating patients with gastric or gastroesophageal junction cancer. Dec 12, 2019 · Background. Marsdenia tenacissima extract (MTE) is a phytochemical widely used as complementary therapy in cancer care. This systematic review was conducted to investigate the anticancer and detoxification effects of MTE, as an adjuvant therapy to …

    Until recently, chemotherapy of gastric cancer was regarded as only marginally active when used with palliative intention or perioperatively. Methods. This is a critical review of the chemotherapy trials being published in gastric carcinoma since 1980. Results Background Advanced gastric cancer can respond to S-1, an oral fluoropyrimidine. We tested S-1 as adjuvant chemotherapy in patients with curatively resected gastric cancer. Methods Patients in Japa...

    Jan 31, 2018В В· Neoadjuvant chemotherapy (NAC) is extensively used in the treatment of patients with gastric cancer (GC), particularly in high risk, advanced gastric cancer. Previous trials testing the efficacy of NAC have reported inconsistent results. This study compares the combined use of NAC and surgery with surgery alone for GC by using a meta-analytic approach. We performed an electronic search of Jan 31, 2018В В· Neoadjuvant chemotherapy (NAC) is extensively used in the treatment of patients with gastric cancer (GC), particularly in high risk, advanced gastric cancer. Previous trials testing the efficacy of NAC have reported inconsistent results. This study compares the combined use of NAC and surgery with surgery alone for GC by using a meta-analytic approach. We performed an electronic search of

    Introduction. Even in after curative surgery and adequate linfoadenectomy the survival of advanced gastric cancer (AGC) remains poor. At present some data have been published on the effects of NACT and perioperative chemotherapy on AGC and Esophago-gastric cancer (EGC) but not definitive ones. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving combination chemotherapy and pembrolizumab may work better in treating patients with gastric or gastroesophageal junction cancer.

    Unlabelled: The five years survival rate for patients with gastric cancer is 15-25%. With the aim of improving survival, chemotherapy has been used in different adjuvant settings. May 01, 2003В В· chemotherapy in the treatment of gastric cancer (Table 3).[14] Adjuvant Chemoradiotherapy Gastric adenocarcinoma has a tendency to recur both locoregionally and distantly following curative resection (Table 4).[34-37] As a result, many investigators have explored the combination of chemotherapy and radiotherapy to prevent tumor recurrence.

    Jul 11, 2013В В· No standard adjuvant or palliative chemotherapy regimen has been internationally approved for patients with advanced gastric cancer. Adjuvant chemoradiotherapy is administered prior to surgery and is used in the Unitied States, and intensified chemotherapy is administered prior to and after surgery and is used in Europe. Jul 13, 2017В В· Efficacy and safety of taxane-based systemic chemotherapy of advanced gastric cancer: A systematic review and meta-analysis in the first-line treatment of metastatic gastric cancer

    Dec 18, 2019В В· Gastric cancer is the fifth most common cancer and the third leading cause of cancer death worldwide, accounting for over 1,000,000 newly diagnosed cancer patients and over 783,000 cancer-related deaths annually [].Radical gastrectomy with extended lymphadenectomy (D2 gastrectomy) is the standard of care for gastric cancer in many countries in East Asia [2, 3]. Background Advanced gastric cancer can respond to S-1, an oral fluoropyrimidine. We tested S-1 as adjuvant chemotherapy in patients with curatively resected gastric cancer. Methods Patients in Japa...

    Aug 29, 2017В В· Gastric cancer is the fifth most common cancer worldwide. In "Western" countries, most people are either diagnosed at an advanced stage, or develop a relapse after surgery with curative intent. In people with advanced disease, significant benefits from targeted therapies are currently limited to HER-2 positive disease treated with trastuzumab, in combination with chemotherapy, in first-line. May 01, 2003В В· chemotherapy in the treatment of gastric cancer (Table 3).[14] Adjuvant Chemoradiotherapy Gastric adenocarcinoma has a tendency to recur both locoregionally and distantly following curative resection (Table 4).[34-37] As a result, many investigators have explored the combination of chemotherapy and radiotherapy to prevent tumor recurrence.

    In western Europe, multidisciplinary perioperative treatment is the standard practice for locally advanced gastric cancer, for which it is crucial to recognise the presence of peritoneal carcinomatosis, differentiate a T2 from a T3 tumour, and view lymph node spread before the initiation of neoadjuvant chemotherapy. Dec 01, 2019В В· The current therapeutic strategy for locally advanced gastric cancer is multidisciplinary with surgical procedure as the core. 1 Since the MAGIC (Medical Research Council Adjuvant Gastric Infusional Chemotherapy) trial, neoadjuvant chemotherapies for gastric cancer have been widely accepted. 2 Possible advantages include better tolerance, tumor